| 主权项 |
1. A compound of the formula (I) in which A represents a bond or —C(R6AR6B)—,
whereR6A represents hydrogen, (C1-C4)-alkyl or trifluoromethyl,R6B represents hydrogen or (C1-C4)-alkyl, R1 represents (C1-C6)-alkyl, (C2-C6)-alkenyl, (C2-C6)-alkynyl or (C3-C7)-cycloalkyl,
where (C1-C6)-alkyl, (C2-C6)-alkenyl and (C2-C6)-alkynyl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of deuterium, halogen, cyano, oxo, hydroxy, trifluoromethyl, (C3-C7)-cycloalkyl, (C1-C6)-alkoxy, trifluoromethoxy and phenyl,
in which (C3-C7)-cycloalkyl may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of (C1-C4)-alkyl, oxo, hydroxy, (C1-C4)-alkoxy and amino,andin which (C1-C6)-alkoxy may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of amino, hydroxy, (C1-C4)-alkoxy, hydroxycarbonyl and (C1-C4)-alkoxycarbonylandin which phenyl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of halogen, cyano, nitro, (C1-C4)-alkyl, trifluoromethyl, hydroxy, hydroxymethyl, (C1-C4)-alkoxy, trifluoromethoxy, (C1-C4)-alkoxymethyl, hydroxycarbonyl, (C1-C4)-alkoxycarbonyl, aminocarbonyl, mono-(C1-C4)-alkylaminocarbonyl and di-(C1-C4)-alkylaminocarbonyl,andwhere (C3-C7)-cycloalkyl may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of fluorine, (C1-C4)-alkyl, (C1-C4)-alkoxy, hydroxy, amino and oxo, R2 represents benzothienyl, phenyl, thienyl or furyl,
where benzothienyl, phenyl, thienyl and furyl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of halogen, cyano, nitro, (C1-C4)-alkyl, trifluoromethyl, hydroxy, (C1-C4)-alkoxy and trifluoromethoxy, R3 represents a group of the formula where
# represents the point of attachment to the nitrogen atom,L represents (C1-C4)-alkanediyl,
where (C1-C4)-alkanediyl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of fluorine and (C1-C4)-alkyl,R7A represents hydrogen or (C1-C4)-alkyl, R7B represents hydrogen or (C1-C4)-alkyl, or
R7A and R7B together with the carbon atom to which they are attached form a 3- to 6-membered carbocycle,R8 represents hydroxycarbonyl, (C1-C4)-alkoxycarbonyl, aminocarbonyl, mono-(C1-C4)-alkylaminocarbonyl or di-(C1-C4)-alkylaminocarbonyl,R9 represents hydroxy, trifluoromethoxy, (C1-C4)-alkoxy, hydroxycarbonyl, (C1-C4)-alkoxycarbonyl, aminocarbonyl, mono-(C1-C4)-alkylaminocarbonyl or di-(C1-C4)-alkylaminocarbonyl, R4 represents phenyl, naphthyl or 5- to 10-membered heteroaryl,
where phenyl, naphthyl and 5- to 10-membered heteroaryl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of halogen, cyano, nitro, (C1-C4)-alkyl, difluoromethyl, trifluoromethyl, hydroxy, (C1-C4)-alkoxy, difluoromethoxy and trifluoromethoxy, R5 represents hydrogen, deuterium, trifluoromethyl or (C1-C4)-alkyl, and its salts, solvates and solvates of the salts. |
