| 发明名称 | miR-31 in duchenne muscular dystrophy therapy | ||
| 摘要 | The invention relates to the therapy of Duchenne Muscular Dystrophy (DMD) by means of modulating the amount of a specific miRNA (miR-31). | ||
| 申请公布号 | US9034838(B2) | 申请公布日期 | 2015.05.19 |
| 申请号 | US201013322023 | 申请日期 | 2010.05.24 |
| 申请人 | UNIVERSITA DEGLI STUDI DI ROMA “LA SAPIENZA” | 发明人 | Bozzoni Irene;Martone Julie;Cacchiarelli Davide;Incitti Tania |
| 分类号 | C12Q1/68;C12N15/113 | 主分类号 | C12Q1/68 |
| 代理机构 | Lucas & Mercanti, LLP | 代理人 | Lucas & Mercanti, LLP |
| 主权项 | 1. A nucleic acid molecule or a derivative thereof wherein the derivative is a DNA molecule coding the nucleic acid molecule and wherein the nucleic acid molecule is: 5′ggcagcuauguuugcaucuugccucacacagcuauguuugcaucuugccucacacagcuauguuugcaucuugccucaca cagcuauguuugcaucuugccuccgc-3′(SEQ ID NO: 4), 5′-gaaauggcaaguuau-3′(SEQ ID NO: 1) or 5′-ccauauaaagaaauggcaaguua-3′ (SEQ ID NO: 2). | ||
| 地址 | Rome IT | ||