Bio-diagnostic testing system and methods

摘要

An implantable diagnostic device in accordance with the present disclosure includes a probe assembly that can be implemented in a variety of ways. A few example implementations include: a needle inside which is located a bio-sensor chip (the needle being insertable into a human being); a compact package containing the bio-sensor chip (the compact package configured for placement inside a catheter); or a silicon-based bio-sensor package configured for insertion into a vein.

主权项

1. A bio-diagnostic system comprising:
a probe assembly configured for insertion into an animate object, the probe assembly comprising: an optical waveguide configured for propagating a light beam; a circular optical resonator incorporating a capture agent placed upon a binding site that is exposed to a fluid, the circular optical resonator configured to receive at least a portion of the propagated light beam and generate therefrom, a first resonant wavelength when no binding reaction is present at the binding site, and a second resonant wavelength when a binding reaction is present at the binding site, the binding reaction modifying a refractive index of the circular optical resonator; a heating element configured for heating the binding site; and a calorimeter for measuring a temperature of the binding site.