Noble metal fine particle, method for withdrawing noble metal fine particles, and method for producing noble metal fine particle dispersed material using withdrawn noble metal fine particles

摘要

The present invention provides a noble metal fine particle with a protein adsorbed thereon, including a noble metal fine particle, and a protein adsorbed on a surface of the noble metal fine particle. The protein has an isoelectric point in a range of pH 4.0 to 7.5. An amount of the protein adsorbed is in a range of 3 to 55.1 wt % with respect to a total weight of the noble metal fine particle and the protein. The noble metal fine particle with a protein adsorbed thereon according to the present invention has excellent redispersibility. That is, by adjusting the pH of a noble metal fine particle dispersed liquid to the isoelectric point of the proteins and allowing the noble metal fine particles to be aggregated without adding a degrading enzyme that degrades the proteins to the noble metal fine particle dispersed liquid, it is possible to allow the noble metal fine particles with proteins adsorbed thereon withdrawn from the noble metal fine particle dispersed liquid to have an average particle diameter that is not increased significantly even after they are redispersed in another dispersion medium.

主权项

1. A method for withdrawing a plurality of fine particles, each fine particle comprising a noble metal fine particle, and a protein adsorbed on a surface of the noble metal fine particle, the method comprising the steps of:
adjusting pH of a noble metal fine particle dispersed liquid that contains a first dispersion medium that is a liquid, and a plurality of fine particles, each fine particle comprising a noble metal fine particle, and a protein adsorbed on a surface of the noble metal fine particle, to an isoelectric point of the protein so that the plurality of the fine particles is aggregated in the first dispersion medium, wherein the isoelectric point of the protein is in a range of pH 4.0 to 7.5, and an amount of the protein adsorbed is in a range of 3 to 55.1 wt % with respect to a total weight of the noble metal fine particle and the protein, and the liquid contains no degrading enzyme that degrades the protein; and withdrawing the plurality of the fine particles from the first dispersion medium by a solid-liquid separation operation.