Cannula for minimizing dilution of dosing during nitric oxide delivery

摘要

The present invention generally relates to, amongst other things, systems, devices, materials, and methods that can improve the accuracy and/or precision of nitric oxide therapy by, for example, reducing the dilution of inhaled nitric oxide (NO). As described herein, NO dilution can occur because of various factors. To reduce the dilution of an intended NO dose, various exemplary nasal cannulas, pneumatic configurations, methods of manufacturing, and methods of use, etc. are disclosed.

主权项

1. A nasal cannula for therapeutic gas delivered to a patient in need thereof, the nasal cannula comprising:
a nitric oxide lumen and an oxygen lumen:
the nitric oxide lumen being a first therapeutic gas lumen for delivering a first therapeutic gas comprising nitric oxide to a patient, andthe oxygen lumen being a second therapeutic gas lumen for delivering a second therapeutic gas comprising oxygen to the patient; and the nitric oxide lumen and the oxygen lumen aggregating at a cannula nosepiece, the cannula nosepiece having separate flow paths to the patient for (i) the nitric oxide lumen and (ii) the oxygen lumen such that the flow path for the first therapeutic gas delivers the first therapeutic gas to both a first nostril and a second nostril of a patient and the flow path for the second therapeutic gas delivers the second therapeutic gas to both the first and second nostrils of the patient without mixing the first therapeutic gas and the second therapeutic gas in the cannula nosepiece when connected to a first gas source comprising nitric oxide and a second gas source comprising oxygen; and the flow path for the first therapeutic gas at the cannula nosepiece having an inner diameter that is smaller than an inner diameter of the nitric oxide lumen.