| 发明名称 |
INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND P53 |
| 摘要 |
<p>The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, s, t, R1, R2, A and Z have defined meanings. (see formula I)</p> |
| 申请公布号 |
CA2644643(C) |
申请公布日期 |
2015.05.19 |
| 申请号 |
CA20072644643 |
申请日期 |
2007.03.19 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
LACRAMPE, JEAN FERNAND ARMAND;MEYER, CHRISTOPHE;SCHOENTJES, BRUNO;LARDEAU, DELPHINE YVONNE RAYMONDE;PONCELET, ALAIN PHILIPPE;VAN HIJFTE, LUC |
| 分类号 |
C07D401/12;A61K31/4409;A61P35/00;C07D405/12;C07D471/04 |
主分类号 |
C07D401/12 |
| 代理机构 |
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代理人 |
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| 主权项 |
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