| 发明名称 | Medicament for therapeutic treatment and/or improvement of sepsis | ||
| 摘要 | A medicament for therapeutic treatment and/or improvement of sepsis in a patient with severe sepsis accompanied with one or more organ dysfunctions, wherein a value of International Normalized Ratio (INR) of a plasma specimen obtained from said patient is more than 1.4, which comprises thrombomodulin as an active ingredient. | ||
| 申请公布号 | US9034823(B2) | 申请公布日期 | 2015.05.19 |
| 申请号 | US201414283976 | 申请日期 | 2014.05.21 |
| 申请人 | ASAHI KASEI PHARMA CORPORATION | 发明人 | Tsuruta Kazuhisa;Aoki Yoshikazu;Osawa Yutaka;Kaul Inder |
| 分类号 | A61K38/36;A61K38/57;A61K38/17;A61K38/00;C12N15/09 | 主分类号 | A61K38/36 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A method for therapeutic treatment of severe sepsis with coagulopathy, which comprises the step of: intravenously administering thrombomodulin to a patient having severe sepsis with coagulopathy when a value of International Normalized Ratio (INR) of a plasma specimen obtained from said patient is more than 1.4, wherein said patient has one or more organ dysfunctions selected from the group consisting of liver dysfunction, kidney dysfunction, respiratory organ dysfunction and circulatory organ dysfunction. | ||
| 地址 | Tokyo JP | ||