发明名称 Process for preparation of a herbal extract
摘要 A process for preparing an extract of Momordica charantia, including: a) preparing crude juice; b) filtering to obtain filtered juice; c) modifying pH; d) allowing the pH modified juice to stabilize; e) neutralizing the stabilized juice; f) allowing the neutralized juice to stand for 20-30 minutes; g) rechecking the pH level; and h) drying the juice to obtain the extract. The process said above is simple, cost effective, which does not employ any harmful organic solvents and which enhances the potency of the constituents. A simple and potent formulation showing anti-diabetic activity comprising active constituents of Momordica charantia is also provided.
申请公布号 US9034400(B2) 申请公布日期 2015.05.19
申请号 US201213982223 申请日期 2012.01.27
申请人 Piramal Enterprises Limited 发明人 Sharma Somesh;Chauhan Vijay Singh;Suthar Ashish
分类号 A61K36/42;A61K36/00;A61K9/16;A61K9/20;A61K9/48 主分类号 A61K36/42
代理机构 Osha Liang LLP 代理人 Osha Liang LLP
主权项 1. A process for preparing an extract of Momordica charantia comprising the following sequential steps: (a) crushing and chopping unripe fresh fruit of Momordica charantia to which water is added intermittently to produce a crude juice; (b) filtering the crude juice to obtain a filtered juice; (c) acidifying the filtered juice to a pH between 2.5 and 4 to produce an acidified juice by adding at least one organic acid selected from the group consisting of citric acid, acetic acid, lactic acid, tartaric acid, oxalic acid and lemon juice; (d) stabilizing the pH of the acidified juice by allowing it to stand for 5 to 25 minutes to produce a stabilized juice; (e) neutralizing the stabilized juice to produce a neutralized juice by adding at least one alkali selected from the group consisting of sodium hydroxide, potassium hydroxide, calcium hydroxide and sodium bicarbonate; (f) allowing the neutralized juice to stand for a period of 20 to 30 minutes; (g) rechecking the pH level of the juice for neutralization; and (h) drying the neutralized juice to obtain dried extract of Momordica charantia.
地址 Mumbai IN