Aminoethylation process having improved yield of aryloxyalkylene amine compounds and reduced urea by-products

摘要

Disclosed is a process for preparing an aryloxyalkylene amine compound via an aminoethylation reaction comprising: a) reacting an aromatic hydroxyl compound in the presence of a basic catalyst with a 2-oxazolidinone compound of the formula II to form an intermediate reaction product;;wherein R3 is selected from the group consisting of hydrogen or lower alkyl having 1 to 6 carbon atoms, R4 is selected from the group consisting of hydrogen, straight or branched chain alkyl having from one to six carbon atoms, phenyl, alkaryl, or arylalkyl; and b) reacting the intermediate product of step a) with a polyalkylene polyamine.

主权项

1. A process for preparing an aryloxyalkylene amine compound via an aminoethylation reaction comprising:
a) reacting an aromatic hydroxyl compound in the presence of a basic catalyst with a 2-oxazolidinone compound of the formula II to form an intermediate reaction product; wherein R3 is selected from the group consisting of hydrogen or lower alkyl having 1 to 6 carbon atoms, R4 is selected from the group consisting of hydrogen, straight or branched chain alkyl having from one to six carbon atoms, phenyl, alkaryl, or arylalkyl; wherein the intermediate product contains at least one dialkylene urea compound; and b) reacting the intermediate product of step a) with a polyalkylene polyamine; wherein at least a portion of the dialkylene urea compound is converted to the aryloxyalkylene amine compound.