发明名称 |
CRYSTALLINE FORMS OF A FACTOR XIA INHIBITOR |
摘要 |
<p>The instant invention provides crystalline forms of (S,E)-4-(2-(3-(3-chloro-2-fluoro-6-(1H-tetrazol-1-yl)phenyl)acryloyl)-5-(4-methyl-2-oxopiperazin-1-yl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid and its solvates thereof; processes for the production of such crystalline forms; pharmaceutical compositions comprising such crystalline forms; and methods of treating thromboembolic disorders with such crystalline forms or such pharmaceutical compositions.</p> |
申请公布号 |
PH12015500678(A1) |
申请公布日期 |
2015.05.18 |
申请号 |
PH12015500678 |
申请日期 |
2015.03.26 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
DABROS, MARTA;WEI, CHENKOU |
分类号 |
A61K31/496;A61P7/02;C07D401/14 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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