发明名称 |
RADIOACTIVE HALOGEN LABELED COMPOUNDS OR SALTS THEREOF, AND PHARMACEUTICALS CONTAINING THE SAME |
摘要 |
<p>PROBLEM TO BE SOLVED: To provide: radioactive halogen labeled compounds which have high selectivity for aldosterone synthase (CYP11B2) over steroid 11β-hydroxylase (CYP11B1) and high accumulation selectivity in the adrenal gland compared to the surrounding organs; and diagnostic imaging agents containing the compounds.SOLUTION: The present invention provides radioactive halogen labeled compounds represented by the formula (1) in the figure, and diagnostic imaging agents containing the compounds. [In the formula, Ris a halogen atom or -(CH)OH, and Ris a halogen atom, a nitro group or a cyano group, provided that one of Rand Ris a radioactive halogen atom.]</p> |
申请公布号 |
JP2015093833(A) |
申请公布日期 |
2015.05.18 |
申请号 |
JP20130231954 |
申请日期 |
2013.11.08 |
申请人 |
NIHON MEDI PHYSICS CO LTD;KYOTO UNIV |
发明人 |
OKUMURA YUKI;IZAWA AKIHIRO;AKAMA KEI;KOBASHI SHINYA;ABE TSUTOMU;SAJI HIDEO;KIMURA HIROYUKI |
分类号 |
C07D233/64;A61K51/00;C07B59/00;C07D233/68;C07F7/10;C07F7/22 |
主分类号 |
C07D233/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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