发明名称 RADIOACTIVE HALOGEN LABELED COMPOUNDS OR SALTS THEREOF, AND PHARMACEUTICALS CONTAINING THE SAME
摘要 <p>PROBLEM TO BE SOLVED: To provide: radioactive halogen labeled compounds which have high selectivity for aldosterone synthase (CYP11B2) over steroid 11β-hydroxylase (CYP11B1) and high accumulation selectivity in the adrenal gland compared to the surrounding organs; and diagnostic imaging agents containing the compounds.SOLUTION: The present invention provides radioactive halogen labeled compounds represented by the formula (1) in the figure, and diagnostic imaging agents containing the compounds. [In the formula, Ris a halogen atom or -(CH)OH, and Ris a halogen atom, a nitro group or a cyano group, provided that one of Rand Ris a radioactive halogen atom.]</p>
申请公布号 JP2015093833(A) 申请公布日期 2015.05.18
申请号 JP20130231954 申请日期 2013.11.08
申请人 NIHON MEDI PHYSICS CO LTD;KYOTO UNIV 发明人 OKUMURA YUKI;IZAWA AKIHIRO;AKAMA KEI;KOBASHI SHINYA;ABE TSUTOMU;SAJI HIDEO;KIMURA HIROYUKI
分类号 C07D233/64;A61K51/00;C07B59/00;C07D233/68;C07F7/10;C07F7/22 主分类号 C07D233/64
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