| 发明名称 |
GTP Sensors |
| 摘要 |
Certain embodiments are directed to polypeptide sensors. Certain aspects of the invention are directed to polypeptides for sensing or detecting GTP and GTP concentrations. In further aspects, the polypeptide sensor can measure GTP concentrations, with high temporal and spatial resolution. |
| 申请公布号 |
US2015135343(A1) |
申请公布日期 |
2015.05.14 |
| 申请号 |
US201314402077 |
申请日期 |
2013.05.18 |
| 申请人 |
The Board of Regents of the University of Texas System |
发明人 |
Sousa Rui;Rana Mitra |
| 分类号 |
G01N33/53;C07K14/245;C07K14/435;G01N33/58 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A polypeptide comprising an amino terminal GTP binding domain coupled to a central conformation sensitive fluorescent protein domain that is coupled to a carboxy terminal guanine-dissociation inhibitor domain, wherein fluorescence of the polypeptide changes upon binding to GTP. |
| 地址 |
Austin TX US |
