发明名称 |
METHODS AND KITS FOR DIAGNOSING HEPARIN-INDUCED THROMBOCYTOPENIA |
摘要 |
Provided herein are methods for diagnosing heparin-induced thrombocytopenia (HIT) in a subject. The methods comprise (a) contacting a PF4-heparin complex with a biological sample from the subject; (b) contacting the composition of part (a) with an HIT-like antibody; and (c) measuring the amount of bound HIT-like antibody. In one embodiment, a significant decrease in the amount of bound HIT-like antibody in the composition of part (b) as compared to a control level is indicative of a diagnosis of HIT in the subject. Also provided are assay kits for performing the methods of the invention. |
申请公布号 |
US2015132778(A1) |
申请公布日期 |
2015.05.14 |
申请号 |
US201314397875 |
申请日期 |
2013.04.30 |
申请人 |
The Trustees of the University of Pennsylvania |
发明人 |
Cines Douglas B.;Cuker Adam;Sachais Bruce |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
|
代理人 |
|
主权项 |
1. (canceled) |
地址 |
Philadelphia PA US |