| 摘要 |
PROBLEM TO BE SOLVED: To provide antibodies which inhibit an action of Interleukin 1α, which is an inflammatory cytokine which plays a role in a number of different functions including inflammation, immune response, tumor metastasis, and hematopoiesis, and inhibit diseases such as atherosclerosis.SOLUTION: The invention provides a composition containing a purified human IgG1 monoclonal antibody which specifically binds to human interleukin 1α, and a pharmacologically acceptable additive. The monoclonal antibody is at least 90 wt.% purity except the additive, and has 1×10Mor more of Ka. |
