| 发明名称 |
PRODUCTION OF FATTY ALCOHOLS FROM ENGINEERED MICROORGANISMS |
| 摘要 |
The invention generally relates to the production of a fatty alcohol composition from recombinant microbial cells. The fatty alcohols are produced by expressing a gene encoding a heterologous fatty alcohol forming acyl-CoA reductase (“FAR”); a gene encoding a heterologous thioesterase (“TE”) gene and a gene encoding an acyl-CoA synthetase (“ACS”). |
| 申请公布号 |
US2015133698(A1) |
申请公布日期 |
2015.05.14 |
| 申请号 |
US201314394817 |
申请日期 |
2013.04.19 |
| 申请人 |
Codexis, Inc. |
发明人 |
Chan Kaman;Valle Fernando;Barak Yoram;Clark Louis;Karlshoej Kristian |
| 分类号 |
C07C31/125;A61Q19/00;C11D3/20;C12P7/64;C12P5/02;A61K8/34;C12P7/04 |
主分类号 |
C07C31/125 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A recombinant bacterial microbial culture that produces a composition of fatty alcohols said fatty alcohol composition comprising fatty alcohols having a carbon chain length of at least 60% of C12, C14 and C16 fatty alcohols, the culture comprising a recombinant bacterial microorganism comprising (a) a gene encoding a heterologous thioesterase (“TE”); (b) a gene encoding a heterologous fatty alcohol forming acyl-CoA reductase (“FAR”) and (c) an over-expressed acyl-CoA synthetase (“ACS”). |
| 地址 |
Redwood City CA US |
