The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein Z
申请公布号
AU2012279236(B2)
申请公布日期
2015.05.14
申请号
AU20120279236
申请日期
2012.06.29
申请人
GILEAD SCIENCES, INC.
发明人
CORKEY, BRITTON KENNETH;ELZEIN, ELFATIH;JIANG, ROBERT H.;KALLA, RAO V.;KOLTUN, DMITRY;LI, XIAOFEN;MARTINEZ, RUBEN;PARKHILL, ERIC Q.;PERRY, THAO;ZABLOCKI, JEFF;VENKATARAMANI, CHANDRASEKAR;GRAUPE, MICHAEL;GUERRERO, JUAN