发明名称 |
SYSTEMS AND METHODS FOR EXTRACORPOREAL BLOOD MODIFICATION |
摘要 |
The present invention generally relates to systems and methods for targeted removal of a substance or biomolecule such as a protein from a biological fluid, such as blood. In some cases, the blood may be withdrawn from a subject, treated, and returned to the subject. Previous techniques for removal of biological materials from blood, such as hemodialysis and plasmapheresis, were generally non-specific (i.e., they removed a multitude of proteins/toxins from the blood). By contrast, novel methods and devices described herein are capable of removing specific or single substances such as proteins from biological fluids such as blood in a specific manner. Such highly specific protein removal has a broad array of clinical applications, including treatment of inflammatory conditions and autoimmune diseases. |
申请公布号 |
US2015132312(A1) |
申请公布日期 |
2015.05.14 |
申请号 |
US201314400606 |
申请日期 |
2013.03.14 |
申请人 |
Children's Medical Center Corporation |
发明人 |
McAlvin James B.;Mizrahi Boaz;Kohane Daniel S.;Wylie Ryan G. |
分类号 |
A61M1/36;A61L29/06;A61L29/16;A61M5/14 |
主分类号 |
A61M1/36 |
代理机构 |
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代理人 |
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主权项 |
1. A device, comprising:
a chamber component of an extracorporeal circuit, the chamber comprising a surface and an antibody or antigen-binding fragment thereof or a ligand or a receptor bound to the surface. |
地址 |
Boston MA US |