发明名称 |
PYRROLO PYRIMIDINE DERIVATIVE |
摘要 |
The compound represented by general formula (I) has strong Axl inhibition activity by means of a pyridone ring structure being introduced into a pyrrolo pyrimidine skeleton, and so the result can serve as a treatment agent for Axl-related diseases, for example cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glial tumors, renal disease, immune system disorders, and cardiovascular disease. |
申请公布号 |
WO2015068767(A1) |
申请公布日期 |
2015.05.14 |
申请号 |
WO2014JP79461 |
申请日期 |
2014.11.06 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
INUKAI, TAKAYUKI;TAKEUCHI, JUN;YASUHIRO, TOMOKO;WOLF, MARK ALLAN;PAWAL, VIJAY DATTARAM;CHAKRABARTI, ANJAN;CHITTIMALLA, SANTHOSH KUMAR |
分类号 |
C07D487/04;A61K31/519;A61P9/00;A61P13/12;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P43/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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