NOVEL USE OF A DIMETHYL SULPHOXIDE (DMSO) EXTRACT OR FRACTION FROM GRAPTOPETALUM SP.

摘要

Provided is a new approach for treating a metabolic disease, such as diabetes, obesity or fatty liver disease using a dimethyl sulfoxide (DMSO) extract or fraction from Graptopetalum sp. or Rhodiola sp., or an active compound isolated from the DMSO extract or fraction. Also it provided the use of the DMSO extract or fraction from Graptopetalum sp. or Rhodiola sp., or the active compound isolated from the DMSO extract or fraction in activating AMPK pathway and autophagy pathway, which can be used in prevention or treatment of a neurodegenerative disease or amyloid-related disease, such as Alzheimer's disease.