| 发明名称 |
BIOMIMETIC COATING OF MAGNESIUM ALLOY FOR ENHANCED CORROSION RESISTANCE AND CALCIUM PHOSPHATE DEPOSITION |
| 摘要 |
The invention relates to biomimetic peptide-containing compositions for use, in particular, for application and or deposition on a magnesium alloy, e.g., substrate, to at least partially coat a surface of the magnesium alloy. The invention also relates to the coated magnesium alloy which is particularly useful for tissue and bone repair and regeneration applications, such as, for constructing medical implant devices. |
| 申请公布号 |
US2015132356(A1) |
申请公布日期 |
2015.05.14 |
| 申请号 |
US201414540575 |
申请日期 |
2014.11.13 |
| 申请人 |
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
BENIASH ELIA;Sfeir Charles S. |
| 分类号 |
A61L27/34;A61L27/22;A61L27/50;C07K14/47;A61L27/54 |
主分类号 |
A61L27/34 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition for coating magnesium alloy, comprising:
a peptide selected from the group consisting of: DEDE(SSD)nDEG, wherein n is an integer from 2 to 20, indicated by SEQ NO. 1; RRRDEDE(SSD)nDEG, wherein n is an integer from 2 to 20, indicated by SEQ NO. 2; RRRGDEDE(SSD)nDEG, wherein n is an integer from 2 to 20, indicated by SEQ NO. 3; and LKKLKKLDEDE(SSD)nDEG, wherein n is an integer from 2 to 20, indicated by SEQ NO. 4. |
| 地址 |
PITTSBURGH PA US |
