| 发明名称 |
Vaccine and uses thereof |
| 摘要 |
The present disclosure provides immunogenic compositions, such as vaccines, including DNA vaccines, and uses thereof, e.g., to suppress or prevent an immune response and/or to treat or prevent an autoimmune disease. |
| 申请公布号 |
US2015132302(A1) |
申请公布日期 |
2015.05.14 |
| 申请号 |
US201314398423 |
申请日期 |
2013.05.01 |
| 申请人 |
The University of Sydney ;The Sydney Children's Hospitals Network (Randwick and Westmead) ;The Royal Prince Alfred Hospital |
发明人 |
Alexander Stephen;Wang Yuan Min;Zheng Guoping;Wu Huiling;Harris David Charles Hamlyn;Wang Yiping |
| 分类号 |
C07K14/705;A61K35/39;A61K39/08;A61K39/00;C07K16/28;C07K14/33 |
主分类号 |
C07K14/705 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A recombinant nucleic acid encoding a polypeptide comprising the following linked regions:
(i) a region that binds to a cell surface protein expressed on a dendritic cell; and (ii) a co-stimulatory molecule or an immunogenic fragment thereof. |
| 地址 |
Sydney, New South Wales AU |
