发明名称 |
Anellovirus Genome Quantification as a Biomarker of Immune Suppression |
摘要 |
The present invention relates to the use of the measure of anelloviral load for the determination of immunosuppression. More precisely, the present invention provides a method for characterizing the immunosuppressed or non-immunosuppressed status of a subject, comprising the steps of determining the anelloviral load from a biological sample of the said subject, and determining from the said comparison the immunosuppressed or non-immunosuppressed status. The determination of the immunosuppressed status of the subject can then be used to design or adapt a therapeutic treatment. |
申请公布号 |
US2015132260(A1) |
申请公布日期 |
2015.05.14 |
申请号 |
US201314395105 |
申请日期 |
2013.04.19 |
申请人 |
INSTITUT PASTEUR ;UNIVERSITE PARIS DESCARTES ;ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS ;PATHOQUEST ;ECOLE NATIONALE VETERINAIRE D'ALFORT |
发明人 |
Eloit Marc;Cheval Justine;Hebert Charles;Lecuit Marc |
分类号 |
C12Q1/70 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
1. Method for characterizing the immunosuppressed or non-immunosuppressed status of a subject, comprising the steps of:
a. determining the anelloviral load from a biological sample of the said subject, and b. determining from the comparison of step a) the immunosuppressed or non-immunosuppressed status. |
地址 |
Paris FR |