OLIGONUCLEOTIDE INHIBITORS OF DNA METHYLTRANSFERASES AND THEIR USE IN TREATING DISEASES
摘要
Modified oligonucleotides comprising CpG sites, wherein the cytosine is replaced by cytosine analogs are provided as well as methods of making the oligonucleotides and their use in treating cancer, tumorigenesis and hyper-proliferative disorders.
申请公布号
EP2869852(A2)
申请公布日期
2015.05.13
申请号
EP20130817579
申请日期
2013.07.09
申请人
METHEOR THERAPEUTICS CORPORATION;SLEDZIEWSKI, ANDREW Z.;DEVOS, THEODORE;KOLE, RYSZARD
发明人
SLEDZIEWSKI, ANDREW, Z.;DEVOS, THEODORE;KOLE, RYSZARD