| 发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING TUMOR CELL ACTIVITY |
| 摘要 |
Antibodies which target clusterin, a protein involved in the epithelial-to-mesenchymal transition of carcinoma cells, are identified and characterized. The antibodies may be used to modulate tumour cell activity through binding to clusterin. |
| 申请公布号 |
EP1937815(B1) |
申请公布日期 |
2015.05.13 |
| 申请号 |
EP20060790678 |
申请日期 |
2006.09.13 |
| 申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA |
发明人 |
O'CONNOR-MCCOURT, MAUREEN D.;CANTIN, CHRISTIANE;LENFERINK, ANNE E.G. |
| 分类号 |
C12N15/13;A61K31/00;A61K38/17;A61K39/00;A61K39/395;A61P35/00;C07K16/18;C12N15/12;G01N33/53;G01N33/574 |
主分类号 |
C12N15/13 |
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