发明名称 |
Condensed heterocyclic compound |
摘要 |
The present invention provides a compound having a superior PDE10A inhibitory action and use thereof. The compound is a compound represented by the following formula (I):;
wherein each symbol is as defined in the present specification, or a salt thereof. |
申请公布号 |
US9029388(B2) |
申请公布日期 |
2015.05.12 |
申请号 |
US201214002439 |
申请日期 |
2012.03.15 |
申请人 |
Takeda Pharmaceutical Company Limited |
发明人 |
Taniguchi Takahiko;Kunitomo Jun;Yoshikawa Masato;Hasui Tomoaki;Honda Eiji;Imamura Keisuke;Kamisaki Haruhi;Suzuki Shinkichi;Miura Kasei |
分类号 |
C07D471/14;C07D471/04;C07D519/00 |
主分类号 |
C07D471/14 |
代理机构 |
Wenderoth, Lind & Ponack, L.L.P. |
代理人 |
Wenderoth, Lind & Ponack, L.L.P. |
主权项 |
1. A compound represented by the formula (I-i): wherein R1 is a hydrogen atom or an optionally substituted C1-6 alkyl group, X1 is CH or a nitrogen atom, ring A optionally has a substituent, X2 is CR2 or a nitrogen atom, X3 is CR3 or a nitrogen atom, X4 is CR4 or a nitrogen atom, X5 is CR5 or a nitrogen atom, R2, R3, R4 and R5 are each independently a hydrogen atom or a substituent, ring B is an optionally substituted 5- or 6-membered nitrogen-containing heterocycle (said nitrogen-containing heterocycle optionally further forms a fused ring with a ring other than ring C1), Z5 is ═N— or —N═, ring C1 is an optionally substituted 5-membered ring, Z1, Z3′ and Z4′ are each independently a ring C1-constituting atom selected from a carbon atom and a nitrogen atom, ring D is an optionally substituted 5- or 6-membered ring, and is a single bond or a double bond, or a salt thereof. |
地址 |
Osaka JP |