发明名称 Condensed heterocyclic compound
摘要 The present invention provides a compound having a superior PDE10A inhibitory action and use thereof. The compound is a compound represented by the following formula (I):; wherein each symbol is as defined in the present specification, or a salt thereof.
申请公布号 US9029388(B2) 申请公布日期 2015.05.12
申请号 US201214002439 申请日期 2012.03.15
申请人 Takeda Pharmaceutical Company Limited 发明人 Taniguchi Takahiko;Kunitomo Jun;Yoshikawa Masato;Hasui Tomoaki;Honda Eiji;Imamura Keisuke;Kamisaki Haruhi;Suzuki Shinkichi;Miura Kasei
分类号 C07D471/14;C07D471/04;C07D519/00 主分类号 C07D471/14
代理机构 Wenderoth, Lind & Ponack, L.L.P. 代理人 Wenderoth, Lind & Ponack, L.L.P.
主权项 1. A compound represented by the formula (I-i): wherein R1 is a hydrogen atom or an optionally substituted C1-6 alkyl group, X1 is CH or a nitrogen atom, ring A optionally has a substituent, X2 is CR2 or a nitrogen atom, X3 is CR3 or a nitrogen atom, X4 is CR4 or a nitrogen atom, X5 is CR5 or a nitrogen atom, R2, R3, R4 and R5 are each independently a hydrogen atom or a substituent, ring B is an optionally substituted 5- or 6-membered nitrogen-containing heterocycle (said nitrogen-containing heterocycle optionally further forms a fused ring with a ring other than ring C1), Z5 is ═N— or —N═, ring C1 is an optionally substituted 5-membered ring, Z1, Z3′ and Z4′ are each independently a ring C1-constituting atom selected from a carbon atom and a nitrogen atom, ring D is an optionally substituted 5- or 6-membered ring, and is a single bond or a double bond, or a salt thereof.
地址 Osaka JP