| 发明名称 | Polypeptides, nucleic acid molecule encoding polypeptides, and uses of polypeptides | ||
| 摘要 | A polypeptide, a nucleic acid molecule encoding the polypeptide and a pharmaceutical composition comprising the polypeptide are provided. The polypeptide is as defined in the description, can bind to insulin receptors, and is effective in reducing blood sugar, reducing glycated hemoglobin, and ameliorating hepato-renal disorders caused by diabetes. | ||
| 申请公布号 | US9029326(B2) | 申请公布日期 | 2015.05.12 |
| 申请号 | US201414160791 | 申请日期 | 2014.01.22 |
| 申请人 | China Medical University | 发明人 | Ho Tin-Yun;Hsiang Chien-Yun |
| 分类号 | C07K7/08;A61K38/10;C07K7/06;C07K14/415;A61K38/00 | 主分类号 | C07K7/08 |
| 代理机构 | Ferrells, PLLC | 代理人 | Ferrell Michael W.;Ferrells, PLLC ;Kinney Anna L. |
| 主权项 | 1. An isolated polypeptide consisting of the amino acid sequence of RYKYQX1X2YI (SEQ ID NO: 189) or a homologous amino acid sequence derived from the substitution of a single amino acid in SEQ ID NO: 189, wherein X1 is cysteine or tryptophan and X2 is phenylalanine or tryptophan. | ||
| 地址 | Taichung TW | ||