发明名称 |
Formulação líquida contendo anticorpo de concentração elevada |
摘要 |
The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine. |
申请公布号 |
BRPI0818903(A2) |
申请公布日期 |
2015.05.12 |
申请号 |
BR2008PI18903 |
申请日期 |
2008.12.26 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;F. HOFFMANN-LA ROCHE AG |
发明人 |
TOSHIYUKI MORICHIKA;DAISUKE KAMEOKA;YOSHIMI IMAEDA;TERUTOSHI MAEDA;OLIVER BORIS STAUCH |
分类号 |
A61K39/395;A61K9/08;A61K47/18;A61P43/00 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|