| 发明名称 | Globo H and related anti-cancer vaccines with novel glycolipid adjuvants | ||
| 摘要 | An immunogenic composition containing a glycan conjugate including a carrier protein, and a glycan including Globo H, an immunogenic fragment thereof, or stage-specific embryonic antigen-4 (SSEA-4), wherein the glycan is conjugated with the carrier protein through a linker. | ||
| 申请公布号 | US9028836(B2) | 申请公布日期 | 2015.05.12 |
| 申请号 | US201213568510 | 申请日期 | 2012.08.07 |
| 申请人 | Academia Sinica | 发明人 | Wong Chi-Huey;Wu Chung-Yi;Yu Alice L.;Yu John |
| 分类号 | A61K39/385;A61K39/00;C12N15/113 | 主分类号 | A61K39/385 |
| 代理机构 | Cesari and McKenna, LLP | 代理人 | Cesari and McKenna, LLP |
| 主权项 | 1. An immunogenic composition comprising: (a) a glycan conjugate including a carrier protein, and a glycan comprising Globo H, an immunogenic fragment thereof, or stage-specific embryonic antigen-4 (SSEA-4), wherein the glycan is conjugated with the carrier protein through a linker; and (b) an adjuvant that has the following structure:wherein R is (CH2)7PhF or (CH2)10PhF. | ||
| 地址 | Taipei TW | ||