发明名称 |
NOVEL BETA-ALANINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT. |
摘要 |
<p>The present invention relates to novel beta-alanine derivatives, to the pharmaceutically acceptable salts thereof, and to a pharmaceutical composition comprising same as an active ingredient. The novel beta-alanine derivatives and pharmaceutically acceptable salts thereof according to the present invention may effectively inhibit the activity of DGAT1, which is an enzyme serving as a catalyst in the final step of the synthesis of neutral lipids, and therefore can be effectively used as a pharmaceutical composition for preventing or treating various diseases relating to lipid metabolism belonging to the group consisting of obesity, dyslipidemia, fatty liver, insulin resistance syndrome, and hepatitis.</p> |
申请公布号 |
MX2014012937(A) |
申请公布日期 |
2015.05.11 |
申请号 |
MX20140012937 |
申请日期 |
2013.04.25 |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY |
发明人 |
JIN HEE AHN;PAGIRE H. S.;SANG DAL RHEE;KI YOUNG KIM;WON HOON JUNG;MYUNG-AE BAE;JIN SOOK SONG;KWANG-ROK KIM;HYUN JUNG KWAK |
分类号 |
C07C233/25;A61K31/16;A61P1/16;A61P3/04 |
主分类号 |
C07C233/25 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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