摘要 |
The present invention relates to a process for sterilizing implantable biomaterials. In particular, the invention relates to a process for sterilizing a cross-linked collagen-based biomaterial comprising contacting said cross-linked collagen-based biomaterial with a sterilization solution comprising between 3% and 6% v/v propylene oxide and incubating said biomaterial between 30°C and 55°C for greater than 48 hours; with the proviso that the sterilization solution does not include alcohol. |