| 发明名称 |
PEGYLATED AMYLOID BETA FAB |
| 摘要 |
<p>A method to treat conditions associated with A² peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human A² peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule.</p> |
| 申请公布号 |
PT2121754(E) |
申请公布日期 |
2015.05.11 |
| 申请号 |
PT20080713652T |
申请日期 |
2008.01.09 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
RONALD BRADLEY DEMATTOS;UMA KUCHIBHOTLA;JIRONG LU;KELLY RENEE BALES;THOMAS FRANK BUMOL;CHI-KIN CHOW;RYAN JOHN HANSEN;PETER COLON MCDONNELL |
| 分类号 |
C07K16/18;A61K39/395;A61K47/48;A61P25/28;C12N15/13 |
主分类号 |
C07K16/18 |
| 代理机构 |
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代理人 |
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