发明名称 |
NOVEL POLYPEPTIDES |
摘要 |
The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are specific for the human and rat protease plasma kallikrein and are modified in one or two peptide loops to enhance potency and/or protease resistance. |
申请公布号 |
CA2927554(A1) |
申请公布日期 |
2015.05.07 |
申请号 |
CA20142927554 |
申请日期 |
2014.10.28 |
申请人 |
BICYCLE THERAPEUTICS LIMITED |
发明人 |
TEUFEL, DANIEL;STACE, CATHERINE;WALKER, EDWARD |
分类号 |
B65D77/04;A61K47/48;C07K7/08 |
主分类号 |
B65D77/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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