发明名称 |
THERAPEUTIC DRUG FOR DISEASES RELATED TO ENDOPLASMIC RETICULUM CELL DEATH IN CORNEAL ENDOTHELIUM |
摘要 |
The present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress. Specifically, the present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress in the corneal epithelium, the drug containing a TGFβ-signal inhibitor. As a preferred TGFβ-signal inhibitor, the drug contains 4-[4-(1,3-benzodioxole-5-yl)-5-(2-pyridinyl)-1H-imidazole-2-yl]benzamide. |
申请公布号 |
WO2015064768(A1) |
申请公布日期 |
2015.05.07 |
申请号 |
WO2014JP79513 |
申请日期 |
2014.10.30 |
申请人 |
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION;THE DOSHISHA;SENJU PHARMACEUTICAL CO., LTD. |
发明人 |
KOIZUMI, NORIKO;OKUMURA, NAOKI;KINOSHITA, SHIGERU |
分类号 |
A61K45/00;A61K31/437;A61K31/4439;A61K31/444;A61K31/4709;A61K31/519;A61K31/713;A61K48/00;A61P27/02;A61P43/00 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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