发明名称 |
METHODS TO ESTABLISH AND RESTORE NORMAL GUT MICROBIOTA FUNCTION OF SUBJECT IN NEED THEREOF |
摘要 |
The present invention provides a method to define normal maturation of the gut microbiota using a limited number of bacterial taxa found in the gut microbiota. Regressing the relative abundance of age-discriminatory taxa in their gut microbiota against the chronological age of each healthy subject at the time a sample of the gut microbiota was collected produces a regression model that may be used to characterize the maturity of another subject's gut microbiota to provide a measure of gastrointestinal health without having to query the whole microbiota. The present invention also provides composition and methods for preventing and/or treating a disease in a subject in need thereof. |
申请公布号 |
WO2015066625(A1) |
申请公布日期 |
2015.05.07 |
申请号 |
WO2014US63711 |
申请日期 |
2014.11.03 |
申请人 |
WASHINGTON UNIVERSITY |
发明人 |
GORDON, JEFFREY I.;SUBRAMANIAN, SATHISH;HSIAO, ANSEL |
分类号 |
C12Q1/04;G01N33/15 |
主分类号 |
C12Q1/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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