APPARATUS TO PREVENT REPERFUSION INJURY

摘要

Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.

主权项

1. An apparatus to prevent reperfusion injury within an arterial vessel, the apparatus comprising:
an elongated catheter having a proximal region and a distal region, the distal region for advancement within an arterial vessel to a region proximal to a lesion; and a guidewire disposed within a first lumen formed within the elongated catheter, the guidewire slideable within the first lumen to extend a substantial length past the distal region of the elongated catheter, wherein the elongated catheter is trackable over the guidewire to advance the elongated catheter within the arterial vessel to the region proximal to the lesion, wherein the guidewire is to release an anti-reperfusion drug through a distal tip opening in a distal terminal end of the guidewire, wherein, during release, an outer surface of the guidewire is exposed through the lesion.