POLYPEPTIDE COMPOSITION, AND CULTURE METHOD FOR PLURIPOTENT STEM CELL USING SAME

摘要

Provided are a polypeptide composition capable of inducing the cell culture performance, and particularly superior cell proliferation ability, of a pluripotent stem cell, and a culture method for pluripotent stem cells that uses the same. The polypeptide composition contains a prescribed polypeptide including an amino acid sequence derived from a prescribed first region of a human vitronectin or a vitronectin, and in which a multimeric polypeptide, which is a dimer or higher and is intermolecularly crosslinked by a cysteine residue contained in the first region, is included at equal to or less than 20 mass% of the entire mass of polypeptide contained in the composition. The culture method for pluripotent stem cells includes pluripotent stem cells being cultured in the presence of the polypeptide composition, and a cultivator includes a support body equipped with a cell culture surface, and polypeptides that are contained in the polypeptide composition and are placed on the cell culture surface of the support body.