| 发明名称 |
METHOD FOR THE PURIFICATION OF PROSTAGLANDINS |
| 摘要 |
The present invention provides a method for the purification of a prostaglandin by supercritical fluid chromatography, said method comprising the use of a stationary phase and a mobile phase comprising carbon dioxide, provided that when the stationary phase is unmodified silica gel, the prostaglandin is not luprostiol. The invention also provides prostaglandins obtainable by the method. |
| 申请公布号 |
US2015126764(A1) |
申请公布日期 |
2015.05.07 |
| 申请号 |
US201514594668 |
申请日期 |
2015.01.12 |
| 申请人 |
Johnson Matthey Public Limited Company |
发明人 |
HOGAN Robert R.;Rossi Ronald |
| 分类号 |
C07C405/00 |
主分类号 |
C07C405/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A latanoprost composition comprising C11-beta isomer of latanoprost in an amount greater than 0% and less than 0.03%, and containing less than 0.03% C15R-Trans isomer of latanoprost, less than 0.05% C15S-Trans isomer of latanoprost, and less than 0.03% C15S-Cis isomer of latanoprost. |
| 地址 |
London GB |
