METHOD FOR PROCESSING OF STABLE EMULSIONS FROM WHOLE-CELL BIOTRANSFORMATIONS BY MEANS OF PHASE INVERSION

摘要

A method processes a stable emulsion having components from whole-cell biotransformations such as cells, soluble cell components, organic solvents and/or water. In this connection, the emulsion, which is stable after the biotransformation, is mixed with further parts of organic phase, and subsequently the mixture is continuously stirred until a catastrophic phase inversion of the emulsion takes place while mixing; subsequently, this phase-inverted mixture is transferred to a settling container, where the phases of the emulsion separate from one another and can be separated from one another.

主权项

1. A method for processing of a stable emulsion having components from a whole-cell biotransformation comprising:
a) forming a mixture by mixing the emulsion with further parts of a dispersed phase, wherein the emulsion has a plurality of phases and is a stable emulsion after the biotransformation; b) subsequently continuously stirring the mixture until a catastrophic phase inversion of the emulsion takes place while mixing to form a phase-inverted mixture; and c) subsequently transferring the phase-inverted mixture to a settling container where the phases of the emulsion separate from one another and can be removed from one another.