Method of Blood Pooling and Storage

摘要

The disclosure provides methods of making a cell-containing product having a uniform amount of cells therein. The method comprises pooling red blood cells from a plurality of blood units, and inactivating any pathogen contained therein. A storage solution added to the cellular component results in a cell-containing product that is essentially pathogen and white blood cell free and has an extended shelf life of about 42 to about 100 days. The cell-containing product is further divided into units which comprise a uniform dose of RBCs per unit.

主权项

1. A method for preparing a red blood cell (RBC)-containing product from a plurality of blood units comprising:
a) separating a RBC component from the plurality of blood units, wherein the blood unit or the RBC component has been leukoreduced; b) pooling the leukoreduced RBC components from the plurality of blood units; c) treating the RBC component to inactivate one or more pathogens; and d) adding a storage solution to the RBC component; wherein the RBC component in the storage solution provides a RBC-containing product having a storage life of about 42 days to about 100 days.