| 发明名称 |
NOVEL SUBSTITUTED 2-AMINOQUINAZOLIN-4(3H)-ONE DERIVATIVES AS MALARIAL ASPARTIC PROTEASE INHIBITORS |
| 摘要 |
<p>The present invention discloses novel substituted 2-aminoquinazolin-4(3H)-one derivatives and their use as inhibitors of malarial aspartic protease plasmepsin I,II,IV or related malarial aspartic proteases, as well as pharmaceutical compositions thereof for treatment of malaria.</p> |
| 申请公布号 |
WO2015063544(A1) |
申请公布日期 |
2015.05.07 |
| 申请号 |
WO2013IB59782 |
申请日期 |
2013.10.30 |
| 申请人 |
LATVIAN INSTITUTE OF ORGANIC SYNTHESIS |
发明人 |
JIRGENSONS, AIGARS;DOMRACEVA, ILONA;KANEPE-LAPSA, IVETA;RASINA, DACE;JAUDZEMS, KRISTAPS;OTIKOVS, MARTINS |
| 分类号 |
C07D405/04;A61K31/505;A61P33/06 |
主分类号 |
C07D405/04 |
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