METHOD FOR FABRICATION OF POROUS FIBROUS MICROSTRUCTURE WITH VARIOUS 3-DIMENSIONAL STRUCTURES

摘要

The present invention relates to a method for fabricating a three-dimensional porous fibrous microstructure, various three-dimensional porous fibrous microstructures fabricated by the method, an apparatus for detecting a biological marker and a drug delivery system comprising the microstructure. The porous fibrous microstructure of the present invention has excellent interconnectivity between pores and micropores and captures and delivers target particles at high efficiency, and thus can be usefully applied to biomedical applications including the detection of a biomarker and drug delivery.

主权项

1. A method for fabricating a three-dimensional porous fibrous microstructure, comprising:
(a) injecting a polymer solution into an injecting member including a syringe pump and a spinneret; (b) spinning the polymer solution, which is injected into the injecting member, through the spinneret using the syringe pump together with the application of voltage, thereby obtaining a polymer fiber; (c) collecting the polymer fiber into a mold; and (d) drying the polymer fiber, and then separating the dried polymer fiber from the mold, thereby obtaining a three-dimensional porous fibrous microstructure.