发明名称 CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF
摘要 Described herein is certain crystalline forms of Compound 3, as well as pharmaceutical compositions employing the crystalline forms. Also provided are particles (e.g., nanoparticles) comprising such crystalline forms or pharmaceutical compositions. In certain examples, the particles are mucus penetrating particles (MPPs). The present invention further relates to methods of treating or preventing diseases using crystalline forms or pharmaceutical compositions.
申请公布号 US2015125535(A1) 申请公布日期 2015.05.07
申请号 US201414530092 申请日期 2014.10.31
申请人 Kala Pharmaceuticals, Inc. 发明人 Enlow Elizabeth;Nguyen Mint Ngoc;Ong Winston
分类号 C07D491/107;A61K47/10;A61K9/14 主分类号 C07D491/107
代理机构 代理人
主权项 1. 7-(3-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinazolin-7-yloxy)propyl)-2-oxa-7-azaspiro[3.5]nonane in crystalline Form A.
地址 Waltham MA US