发明名称 PLANT PROFILIN POLYPEPTIDES FOR USE IN NON-SPECIFIC ALLERGY IMMUNOTHERAPY
摘要 The invention relates to the treatment of a hypersensitivity immune response caused by a non-profilin allergen of a profilin-containing plant material (e.g. grass or tree pollen) by bystander suppression with a plant profilin (e.g. Phl p 12, Bet v 2, or Ole e 2) or a variant thereof. Also the invention features a particular variant of Phl p 12 with two of its cysteine residues replaced with another amino acid to increase its pharmaceutical properties.
申请公布号 US2015126459(A1) 申请公布日期 2015.05.07
申请号 US201314391777 申请日期 2013.04.16
申请人 ALK-Abello A/S 发明人 Lund Kaare;Brimnes Jens;Henmar Helene;Ipsen Hans-Henrik;Mærkedahl Lise Lund;Hansen Gitte Nordskov;Monsalve Clemente Rafael Ignacio
分类号 C07K14/415 主分类号 C07K14/415
代理机构 代理人
主权项
地址 Horsholm DK