INTERLEUKIN-1 (IL-1) INHIBITORS FOR TREATING FERTILITY DISORDERS

摘要

The invention provides IL-1 inhibitors, methods and uses thereof for retaining ovarian follicle reserve in a mammalian subject, treating infertility and improving responsiveness and sensitivity to COH. The invention further provides methods for improving oocyte quality and/or survival, specifically for IVF, and kits for combining COH treatment with the sensitizing IL- inhibitors of the invention.