发明名称 |
RECOMBINANT AVIAN-INFECTIOUS CORYZA VACCINE AND METHOD FOR PRODUCING SAME |
摘要 |
<p>A recombinant avian infectious coryza vaccine and a process for preparing the same are provided. A process for preparing a recombinant avian infectious coryza vaccine which comprises step of constructing E. coli that may produce as an inclusion body a fusion peptide consisting of peptides derived from outer-membrane protein of Avibacterium paragarinarum serotype A and serotype C, step of culturing said E. coli and collecting: and purifying inclusion body from culture, and step of preparing a preparation comprising said purified inclusion body, and an avian infectious coryza vaccine comprising as an active ingredient the fusion peptide. A linker sequence may be inserted between the respective peptides comprising the fusion peptide. For the peptide derived from the serotypes A and C, an amino acid sequence region, of Region 2 or its vicinity responsible for protection from infection may be used.</p> |
申请公布号 |
EP2382985(B1) |
申请公布日期 |
2015.05.06 |
申请号 |
EP20090834924 |
申请日期 |
2009.12.24 |
申请人 |
THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE |
发明人 |
SAKAMOTO, RYUICHI;BABA, SUSUMU;SAKAGUCHI, MASASHI;MIZOKAMI, HIROSHI |
分类号 |
A61K39/02;A61K39/102;A61P31/04;A61P37/04 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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