发明名称 |
PEPTIDE DERIVATIVES WITH THERAPEUTIC ACTIVITY |
摘要 |
<p>Dipeptide compounds containing a histidine residue proved to have interesting blocking activity on secondary products from lipid oxidative stress, in particular on unsaturated aldehydes such as malondialdehyde and hydroxynonenal, which are known to contribute to the inset of quite a number of chronic pathologies such as neurodegenerative, inflammatory chronic, cardiovascular diseases, diabetes complications and cataract.</p> |
申请公布号 |
EP2041157(B1) |
申请公布日期 |
2015.05.06 |
申请号 |
EP20070734839 |
申请日期 |
2007.06.15 |
申请人 |
FLAMMA S.P.A. |
发明人 |
NEGRISOLI, GIANPAOLO;CANEVOTTI, RENATO;ALDINI, GIANCARLO;ORIOLI, MARICA;CARINI, MARINA;VISTOLI, GIULIO |
分类号 |
C07D233/58;A61K38/05;C07D233/64;C07K5/06;C07K5/062;C07K5/065 |
主分类号 |
C07D233/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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