发明名称 7-NITRO-5-PHENYL-1-(PYRROLIDIN-1-YLMETHYL)-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE AND OTHER BENZODIAZEPINE DERIVATIVES
摘要 <p>The present invention describes compounds of formula (I), and in particular the 7- nitro-5-phenyl-1 -(pyrrolidin-1 -ylmethyl)-1 H-benzo[e][1,4]diazepin-2(3H)-one compound and their pharmaceuticall acceptable salts. The compounds of the invention are useful for medical use, particularly as active ingredient potentially useful for the treatment of cerebral ischemia and other disease characterized by deregulation of sodium and calcium homeostasis.</p>
申请公布号 EP2646421(B1) 申请公布日期 2015.05.06
申请号 EP20110801632 申请日期 2011.11.29
申请人 PIGNATARO, GIUSEPPE;ANNUNZIATO, LUCIO;MOLINARO, PASQUALE;SCORZIELLO, ANTONELLA;SECONDO, AGNESE;PANNACCIONE, ANNA;CUOMO, ORNELLA;CANTILE, MARIA;DI RENZO, GIANFRANCO;CALIENDO, GIUSEPPE;SANTAGADA, VINCENZO;SEVERINO, BEATRICE;FIORINO, FERDINANDO 发明人 PIGNATARO, GIUSEPPE;ANNUNZIATO, LUCIO;MOLINARO, PASQUALE;SCORZIELLO, ANTONELLA;SECONDO, AGNESE;PANNACCIONE, ANNA;CUOMO, ORNELLA;CANTILE, MARIA;DI RENZO, GIANFRANCO;CALIENDO, GIUSEPPE;SANTAGADA, VINCENZO;SEVERINO, BEATRICE;FIORINO, FERDINANDO
分类号 C07D243/24;A61K31/5513;A61P9/10;A61P25/28;C07D243/26 主分类号 C07D243/24
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