U1 SNRNP REGULATES GENE EXPRESSION AND MODULATES ONCOGENICITY
摘要
The present invention relates to the discovery of a novel global gene expression regulation mechanism whereby U1 snRNP (U1) protects pre-mRNAs. In one embodiment, the invention includes compositions and methods for regulating gene expression and treating diseases associated with dysregulated gene expression.
申请公布号
EP2866822(A1)
申请公布日期
2015.05.06
申请号
EP20130813188
申请日期
2013.07.05
申请人
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人
DREYFUSS, GIDEON;WAN, LILI;OH, JUNG MIN;PINTO, ANNA MARIA;YOUNIS, IHAB;BERG, MICHAEL, GEORGE