Strontium-82/rubidium-82 generator, method for producing a rubidium-82 comprising diagnostic agent, said diagnostic agent and its use in medicine

摘要

The invention relates to a strontium-82/rubidium-82 generator, comprising a column filled with a cationic exchanger loaded with strontium-82, and having an inlet and an outlet, and a liquid medium, wherein parts of the column, inlet and outlet coming into contact with the liquid medium are iron-free, preferably metal-free, to a method for producing rubidium-82, and to the obtained diagnostic agent.

主权项

1. A strontium-82/rubidium-82 generator, the generator comprising:
a column filled with a cationic exchanger loaded with strontium-82, and having an inlet and an outlet; an elution medium for rubidium-82, wherein the elution medium is a physiological buffer having a pH ranging from 6 to 8.5; and a sterilization medium comprising a suitable concentration of hypochlorite such that the generator can be used for 2 to 6 months at a substantially constant stability, wherein the parts of the column, the inlet and the outlet that come into contact with the elution medium are made of polyetheretherketone (PEEK).