| 主权项 |
1. A method of synthesizing a radiolabeled benzamide on a solid support comprising:
a) selecting a solid support comprising at least one compound attached to said solid support, wherein the compound is selected from the group consisting of:
Poly-(4S,5S)-2-(5-{dibutyl[2-(4-vinylphenyl)ethyl]stannyl}-2,3-dihydrobenzofuran-7-yl)-3,4-dimethyl-5-phenyl-1,3-oxazolidine-co-divinylbenzene;Poly-(4S,5S)-2-(4-{dibutyl[2-(3-vinylphenyl)ethyl]stannyl}phenyl)-3,4-dimethyl-5-phenyl-1,3-oxazolidine-co-divinylbenzene; andPoly-(4S,5S)-2-(4-{dibutyl[2-(4-vinylphenyl)ethyl]stannyl}phenyl)-3,4-dimethyl-5-phenyl-1,3-oxazolidine-co-divinylbenzene; b) reacting said compound with at least one acid to afford a benzoic acid moiety or a carboxylic acid moiety; c) reacting said moiety of said compound attached to said solid support with at least one amine to afford a benzamide bound to a solid support; and d) reacting said benzamide bound to said solid support with a radioisotope; and an oxidant selected from the group consisting of chloramine-T,N-chlorosuccinimide, tert-butylhydroperoxide, iodogen, iodobeads and meta-chloroperbenzoic acid; to yield said radiolabeled benzamide. |
